HAPLN1 Rabbit Monoclonal Antibody-BS9911M

HAPLN1 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9911M-50, BS9911M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P10915

Host: Rabbit

Reactivity: Human, Mouse, Rat, Zebra fish

Applications: WB, ICC/IF, IHC

All Applications: WB: 1:1000-1:5000
IHC/ICC/IF: 1:50-1:200

Background: The human cartilage link protein, also designated HAPLN1, is a member of the hyaluronan and proteoglycan link protein (HAPLN) family of proteins. This family contains 4 proteins with approximately 50% homology. The human cartilage link protein strengthens tissue architecture by using hyaluronic acid to stabilize the aggregates of proteoglycan monomers inside the extracellular cartilage matrix. It is widely expressed in most tissue types except brain tissue where, much like the other human cartilage link protein genes, it is weakly expressed. The HAPLN and the brain-specific CSPG genes, as well as other members of the link module superfamily, appear to have a common ancestral gene origin.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of HAPLN1 and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 40, 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HAPLN1 Rabbit mAb at 1:1000 dilution
Lane 1: BT-20 whole cell lysate
Lane 2: HUVEC whole cell lysate
Lane 3: SW480 whole cell lysate, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-HAPLN1 antibody.Counter stained with hematoxylin., ICC staining HAPLN1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue).Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.

Alternative Name: Hyaluronan and proteoglycan link protein 1; Cartilage-linking protein 1; Cartilage-link protein; Proteoglycan link protein; HAPLN1; CRTL1

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Unmodified