HAS1 Monoclonal Antibody - RA11330

HAS1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11330-50, RA11330-100

Citations, Manuals and MSDS Available upon request.

Background: hyaluronan synthase 1 (HAS1) Homo sapiens Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheuma

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 3036

SWISS: Q8IYH3

Source: Mouse

Research Use Only