Product Description

Haspin Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65541-50, BS65541-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Haspins is a protein family containing a distinctive C-terminal kinase domain and a divergent N-terminus. Haspin homologues occur within a diverse group of eukaryotes, including animals, plants and fungi, which suggests an early evolutionary origin. Haspin, a nuclear protein strongly expressed in male germ cells, is responsible for the phosphorylation of histone H3 at Thr-3. Depletion of Haspin RNA prevents normal alignment of chromosomes at metaphase, suggesting a crucial role for haspin during chromosome segregation. Expression of haspin also occurs in adμlt thymus and bone marrow, with weaker expression in adμlt prostate, intestine, lung, spleen, and lymph node. The gene encoding human haspin maps to chromosome 17p13.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: germ cell associated 2, Germ cell-specific gene 2 protein, GSG2, H-Haspin, Haploid germ cell-specific nuclear protein kinase, HASP_HUMAN, Serine/threonine-protein kinase Haspin.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from mouse Haspin:421-520/754

Dilution: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: Haspin polyclonal Antibody detects endogenous levels of Haspin protein.

Molecular Weight: ~90kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Z0R0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only