HAVR2 rabbit pAb - ES11186

HAVR2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11186-50, ES11186-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 33kD

Human Gene ID: 84868

Human SWISS Prot NO: Q8TDQ0

Subcellular Location: Membrane; Single-pass type I membrane protein. Cell junction. Cell membrane. Localizes to the immunological synapse between CD8+ T-cells and target cells.

Research Use Only