Product Description

HBEGF Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32602-50, RA32602-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor., PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937)., PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active., similarity:Contains 1 EGF-like domain., subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 22

Protein Molecular Weight (kDa): 22

Storage: -20°C/1 year

Human Gene ID: 1839

Human SwissProt Number: Q99075

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only