HBG1/HBG2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52690-60, E-AB-52690-120, E-AB-52690-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: HBG1/HBG2
Target Synonym: A gamma globin; G gamma globin; Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; Hb F Agamma; Hb F Ggamma; hbfagamma; hbfggamma; HBG 1; HBG 2; HBG1; HBG2; HBGA; HBGR; Hemoglobin gamma 1 chain ; Hemoglobin gamma 2 chain ; Hemoglobin gamma A; Hemoglobin gamma A chain ; Hemoglobin gamma G; Hemoglobin gamma G chain ; Hemoglobin gamma regulator of; Hemoglobin subunit gamma 1; Hemoglobin subunit gamma 2; HSGGL 1; HSGGL1; Methemoglobin; PRO 2979; PRO2979
Research Areas: Cardiovascular
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P69891,P69892
Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Concentration: 0.84 mg/mL
Immunogen: Fusion protein of human HBG1/HBG2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Calculated MW: 16 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only