HBG1 rabbit pAb - ES15816

HBG1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15816-50, ES15816-100

Citations, Manuals and MSDS Available upon request.

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human HBG1 AA range: 34-84

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 3047

Human SWISS Prot NO: P69891

Subcellular Location: cytosol, hemoglobin complex,

Research Use Only