HBG1 Rabbit Polyclonal Antibody - RA32603

HBG1 Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA32603-50, RA32603-100 Citations, Manuals and MSDS Available upon request. Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1) . The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1：500-2000 Applications: WB Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 3047 SWISS: P69891 Source: Rabbit Research Use Only