Product Description

HDAC1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18230-60, E-AB-18230-120, E-AB-18230-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HDAC1

Target Synonym: DKFZp686H12203; GON 10; HD1; HDAC 1; HDAC1; HDAC1; Histone deacetylase 1; Reduced potassium dependency yeast homolog like 1; RPD3; RPD3L1

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q13547

Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human HDAC1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Calculated MW: 55 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only