Product Description

HDAC2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11017-50, MB11017-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q92769

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 55 kDa; Observed MW: 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HDAC2 in K562, C6, 3T3 lysates using HDAC2 antibody., Immunocytochemistry analysis of HDAC2 in Hela using HDAC2 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HDAC2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: HDAC2; Histone deacetylase 2; HD2

Immunogen: Recombinant protein of human HDAC2

Conjugate: Unconjugated

Modification: Unmodified