Product Description

HDAC3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25656-50, RA25656-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF/ICC, ELISA

Alternate Names: HDAC3, Histone deacetylase 3, HD3, RPD3-2, SMAP45

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 48

Protein Molecular Weight (kDa): 48

Storage: -20°C/1 year

Human Gene ID: 8841

Human SwissProt Number: O15379

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only