HDAC4 Monoclonal Antibody - RA11356

HDAC4 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11356-50, RA11356-100

Citations, Manuals and MSDS Available upon request.

Background: histone deacetylase 4 (HDAC4) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 9759

SWISS: P56524

Source: Mouse

Research Use Only