HDAC4 Polyclonal Antibody - E-AB-67932

HDAC4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67932-60, E-AB-67932-120, E-AB-67932-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HDAC4

Target Synonym: HDAC4; AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA

Research Areas: Cancer,Cardiovascular,Epigenetics and Nuclear Signaling,Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P56524

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Concentration: 1 mg/mL

Immunogen: A synthetic peptide of human HDAC4

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 106kDa/119kDa

Observed MW: 140kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only