HDAC4 Polyclonal Antibody - RA25658

HDAC4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25658-50, RA25658-100

Citations, Manuals and MSDS Available upon request.

Background: histone deacetylase 4 (HDAC4) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: HDAC4; KIAA0288; Histone deacetylase 4; HD4

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 9759

Protein MW (KDa): 119

SWISS: P56524

Source: Rabbit

Research Use Only