HDAC8 Polyclonal Antibody - RA25667

HDAC8 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25667-50, RA25667-100

Citations, Manuals and MSDS Available upon request.

Background: histone deacetylase 8 (HDAC8) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat; Monkey

GeneID (Human): 55869

Protein MW (KDa): 42

SWISS: Q9BY41

Source: Rabbit

Research Use Only