Product Description

Hemogen Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65720-50, BS65720-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q9BXL5

Host: Rabbit

Reactivity: Human,

Applications: FCM

All Applications: Flow-Cyt=1ug/test

Background: Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level). It can be up-regulated in normal PBMCs by mitogens.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Hemogen Polyclonal Antibody detects endogenous levels of Hemogen protein.

Bioworld Molecular Weight: 55kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: EDAG; EDAG-1; Erythroid differentiation-associated gene protein; HEMGN; HEMGN_HUMAN; Hemogen; Hemopoietic gene protein; Negative differentiation regulator protein.

Immunogen: KLH conjugated synthetic peptide derived from human Hemogen/EDAG:51-150/484

Conjugate: Unconjugated

Modification: Unmodified