Product Description

Heparin Cofactor II Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalogue Numbers: BS65218-50, BS65218-100

Sizes: 50µl, 100µl

Swiss-Prot: P05546

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF/ICC, ELISA

Background: serpin family D member 1(SERPIND1) Homo sapiens This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015],

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: HC-II Polyclonal Antibody detects endogenous levels of HC-II protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of HepG2 cells, using Heparin Cofactor II Antibody. The picture on the right is blocked with the synthesized peptide., Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Heparin Cofactor II Antibody. The picture on the right is blocked with the synthesized peptide.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1

Immunogen: The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II. AA range:41-90

Conjugate: Unconjugated

Modification: Unmodified