Product Description

HERPUD1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8672-50, BS8672-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The accumμlation of unfolded proteins in the endoplasmic reticμlum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumμlation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces mμltiple transcript variants encoding different isoforms. The fμll-length nature of all transcript variants has not been determined.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: Homocysteine-responsive endoplasmic reticμlum-resident ubiquitin-like domain member 1 protein, Methyl methanesμlfonate (MMF)-inducible fragment protein 1, HERPUD1, HERP, KIAA0025, MIF1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human HERPUD1.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: HERPUD1 polyclonal antibody detects endogenous levels of HERPUD1 protein.

Molecular Weight: ~ 44kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15011

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only