HES2 rabbit pAb - ES10672

HES2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10672-50, ES10672-100

Citations, Manuals and MSDS Available upon request.

Background: domain:Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG)., domain:The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins., function:Transcriptional repressor of genes that require a bHLH protein for their transcription., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., similarity:Contains 1 Orange domain., subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family., tissue specificity:Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 54626

Human SWISS Prot NO: Q9Y543

Subcellular Location: Nucleus

Research Use Only