Product Description

Hexokinase 2 Monoclonal Antibody

Catalogue Numbers: MB66522-50, MB66522-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O08528/P27881

Host: Mouse

Reactivity: Mouse, Rat, Monkey

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Hexokinase 2 protein.

Extra Notes: Western blot analysis of Hexokinase 2 expression in NIH3T3 (A), COS7 (B), C6 (C) whole cell lysates.

Bioworld Molecular Weight: ~ 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase

Immunogen: Recombinant human Hexokinase II protein.

Conjugate: Unconjugated

Modification: Unmodified