Product Description

HGF Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66884-50, MB66884-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Hepatocyte Growth Factor was initially discovered as a mitogenic cytokine that induced hepatocyte replication and proliferation . HGF is produced by stromal cells where it is processed by extracellμlar serine proteases into a heterodimer consisting of alpha and beta subunits .Through activation of its receptor, cMET, HGF has a wide range of effects beyond hepatocytes that includes angiogenesis, epithelial cell proliferation and morphogenesis, and tissue protection and regeneration . The HGF-cMET axis has been associated with several diseases, including cancer, where HGF has been shown to promote invasion, metastasis, and drug resistance . These research studies suggest that HGF is a potential diagnostic and therapeutic target.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: HPTA, Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, SF

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HGF. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of HGF protein.

Molecular Weight: ~ 85 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P14210

Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only