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HGK Monoclonal Antibody - RA11368

HGK Monoclonal Antibody - RA11368

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$198.00 USD
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HGK Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: RA11368-50, RA11368-100

Citations, Manuals and MSDS Available upon request.

Condition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Store at: -20°C/1 year

Recommended Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification Technology: Affinity purification

Alternative Names: MAP4K4, HGK, KIAA0687, NIK, Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase

Background: mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Applications: WB, ELISA

Species Cross-Reactivity: Human

GeneID (Human): 9448

SWISS: O95819

Source: Mouse

Immunogen: Purified recombinant fragment of HGK (aa400-500) expressed in E. Coli.

Category: Monoclonal

Research Use Only