HIF-1α Mouse Monoclonal Antibody (Mix-mA) - RA11373

HIF-1α Mouse Monoclonal Antibody (Mix-mA)

Size: 50μL, 100μL

Catalogue Numbers: RA11373-50, RA11373-100

Citations, Manuals and MSDS Available upon request.

Background: hypoxia inducible factor 1 alpha subunit (HIF1A) Homo sapiens This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.54% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3091

Protein MW (KDa): 110-120

SWISS: Q16665

Source: Mouse

Research Use Only