Product Description

HIF-1β Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21026-50, RA21026-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: aryl hydrocarbon receptor nuclear translocator (ARNT) Homo sapiens This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section)

Alternate Names: ARNT, BHLHE2, Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Class E basic helix-loop-helix protein 2, bHLHe2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta

Clonality: Polyclonal

Dilution: WB: 1:1000-2000 IHC: 1:200-500

Molecular Weight: 87

Protein Molecular Weight (kDa): 87

Storage: -20°C/1 year

Human Gene ID: 405

Human SwissProt Number: P27540

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Research Use Only