Product Description

HIF-1 β/ARNT Monoclonal Antibody (4C5)

Sizes: 50μL, 100μL

Catalogue Numbers: RA11370-50, RA11370-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: aryl hydrocarbon receptor nuclear translocator (ARNT) Homo sapiens This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],

Reactivity: Mouse

Host: Mouse

Applications: WB, IHC-p, IF(paraffin section)

Alternate Names: ARNT, BHLHE2, Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Class E basic helix-loop-helix protein 2, bHLHe2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta

Clonality: Monoclonal

Dilution: WB 1:1000-2000, IHC 1:100-200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 405

Protein Molecular Weight（KDa): 87

Molecular Weight: 87

Research Use Only