HIF-1 β/ARNT Monoclonal Antibody (4C5) - RA11370

HIF-1 β/ARNT Monoclonal Antibody (4C5)

Size: 50μL, 100μL

Catalogue Numbers: RA11370-50, RA11370-100

Citations, Manuals and MSDS Available upon request.

Background: aryl hydrocarbon receptor nuclear translocator (ARNT) Homo sapiens This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Mouse

GeneID (Human): 405

Protein MW (KDa): 87

SWISS: P27540

Source: Mouse

Research Use Only