Product Description

HIF Prolyl Hydroxylases Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12058-50, MB12058-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9NXG6

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 57 kDa; Observed MW: 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HIF Prolyl Hydroxylases in Hela, A549, HL-60, U251, U87-MG lysates using HIF Prolyl Hydroxylases antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using HIF Prolyl Hydroxylases antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: PH4; PH-4; PHD4; EGLN4; HIDEA; HIFPH4; P4H-TM

Immunogen: A synthetic peptide of human HIF Prolyl Hydroxylases

Conjugate: Unconjugated

Modification: Unmodified