Product Description

HIPK3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32645-50, RA32645-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors., PTM:Autophosphorylated, but autophosphorylation is not required for catalytic activity., PTM:May be sumoylated., similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily., similarity:Contains 1 protein kinase domain., subunit:Interacts with Nkx1-2. Interacts with FAS and DAXX. Probably part of a complex consisting of HIPK3, FAS and FADD. Interacts with and stabilizes ligand-bound androgen receptor (AR) (By similarity). Interacts with UBL1/SUMO-1., tissue specificity:Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 133

Protein Molecular Weight (kDa): 133

Storage: -20°C/1 year

Human Gene ID: 10114

Human SwissProt Number: Q9H422

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only