HisRS Polyclonal Antibody - RA25708

HisRS Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25708-50, RA25708-100

Citations, Manuals and MSDS Available upon request.

Background: histidyl-tRNA synthetase (HARS) Homo sapiens Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: HARS; HRS; Histidine--tRNA ligase; cytoplasmic; Histidyl-tRNA synthetase; HisRS

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 3035

Protein MW (KDa): 60

SWISS: P12081

Source: Rabbit

Research Use Only