Histamine H1 Receptor Polyclonal Antibody - RA25710

Histamine H1 Receptor Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25710-50, RA25710-100

Citations, Manuals and MSDS Available upon request.

Background: histamine receptor H1 (HRH1) Homo sapiens Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: HRH1; Histamine H1 receptor; H1R; HH1R

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 3269

Protein MW (KDa): 60

SWISS: P35367

Source: Rabbit

Research Use Only