Histone deacetylase 1 Polyclonal Antibody - BT-AP03984

Histone deacetylase 1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03984-20, BT-AP03984-50, BT-AP03984-100

Citations, Manuals and MSDS Available upon request.

Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HDAC1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Histone deacetylase 1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 55103

UniProt Accession: Human: Q13547; Mouse: O09106; Rat: Q4QQW4

Synonyms: HDAC1; RPD3L1; Histone deacetylase 1; HD1

GeneID: Human: 3065; Mouse: 433759; Rat: 297893

Research Use Only