Histone H2A (AcK118) Polyclonal Antibody-BS67181

Histone H2A (AcK118) Polyclonal Antibody

Catalogue Numbers: BS67181-50, BS67181-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P0C0S8; P16104

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 142% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Histone H2A with an acetylation site at K118 protein.

Extra Notes: Western blot analysis of Histone H2A (AcK118) expression in mouse muscle (A), rat kidney (B), rat muscle (C) whole cell lysates.

Bioworld Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p; H2AFX; H2AX; Histone H2A.x; H2a/x

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Histone H2A with an acetylation site at K118. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified