Histone H2A.X (phospho Ser139) Polyclonal Antibody - RA21342

Histone H2A.X (phospho Ser139) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21342-50, RA21342-100

Citations, Manuals and MSDS Available upon request.

Background: H2A histone family member X (H2AFX) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: H2AFX; H2AX; Histone H2A.x; H2a/x

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3014

Protein MW (KDa): 15
19

SWISS: P16104

Source: Rabbit

Research Use Only