Histone H2A.X Polyclonal Antibody - E-AB-70233

Histone H2A.X Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70233-60, E-AB-70233-120, E-AB-70233-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Histone H2A.X

Target Synonym: H2A histone family member X; H2A histone family member X; H2A.FX; H2A.X; H2a/x; H2AFX; H2AX; H2AX; Histone H2A.X

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P16104,P27661

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Concentration: 0.86 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:300-1:800

Calculated MW: 15-18kDa

Observed MW: 18kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only