Histone H2A.X rabbit pAb - ES2525

Histone H2A.X rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2525-50, ES2525-100

Citations, Manuals and MSDS Available upon request.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

Alternate Name: H2AFX; H2AX; Histone H2A.x; H2a/x

Source: Rabbit

Applications: WB; IHC; IF; CoIP; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. IP 1:200-500, ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H2A.X. AA range:94-143

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 3014

Human SWISS Prot NO: P16104

Subcellular Location: Nucleus. Chromosome.

Research Use Only