Product Description

Histone H2A.Z (AcK11) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67177-50, BS67177-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template. Histones thereby play a central role in transcription regμlation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regμlated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Category: Primary Antibody

Reactivity: Human, Zebrafish

Host: Rabbit

Applications: WB

Alternate Names: H2AZ, Histone H2A.Z, H2A/z

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Histone H2A.Z with an acetylation site at K11. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 138% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Histone H2A.Z with an acetylation site at K11 protein.

Molecular Weight: ~ 15 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P0C0S5

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only