Histone H2A.Z Polyclonal Antibody - RA25766

Histone H2A.Z Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25766-50, RA25766-100

Citations, Manuals and MSDS Available upon request.

Background: H2A histone family member Z (H2AFZ) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:1000-2000

Alternative Names: H2AFZ; H2AZ; Histone H2A.Z; H2A/z

Applications: WB

Species Cross-Reactivity: Mouse; Rat

GeneID (Human): 3015

Protein MW (KDa): 14

SWISS: P0C0S5

Source: Rabbit

Research Use Only