Product Description

Histone H2B (AcK116) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67560-50, BS67560-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones ore component of nucleosome .Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template.Histones thereby play a central role in transcription regμlation, DNA repair, DNA replication and chromosomal stability .DNA accessibility is regμlated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling .Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear.

Category: Primary Antibody

Reactivity: Human, Zebrafish

Host: Rabbit

Applications: WB

Alternate Names: HIST1H2BA, TSH2B, Histone H2B type 1-A, Histone H2B testis, Testis-specific histone H2B, HIST1H2BB, H2BFF, Histone H2B type 1-B, Histone H2B.1, Histone H2B.f, H2B/f, HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK, Histone H2B type 1-C/E/F/G/I, Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Histone H2B with an acetylation site at K116. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of Histone H2B with an acetylation site at K116 protein.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96A08, P33778, P62807

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only