Histone H3.3 Polyclonal Antibody - BT-AP04098

Histone H3.3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04098-20, BT-AP04098-50, BT-AP04098-100

Citations, Manuals and MSDS Available upon request.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H3F3A contains introns and its mRNA is polyadenylated, unlike most histone genes. Histone H3. encoded is a replication-independent member of the histone H3 family.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: H3F3A

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Histone H3.3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 15328

UniProt Accession: Human: P84243; Mouse: P84244; Rat: P84245

Synonyms: H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3

GeneID: Human: 3020/3021; Mouse: 15078; Rat: 1.00362e+008

Research Use Only