Product Description

Histone H3 (mono+di+tri methyl K79) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40149-50, BS40149-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template. Histones thereby play a central role in transcription regμlation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regμlated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecμles each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: H3 histone, HIST1H3A, Histone cluster 1, H3a, H3/l, HIST3H3, H3K79me1, H3K79me2, H3K79me3,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Methylated

Immunogen: A synthesized peptide derived from human Histone H3 (mono+di+tri methyl K79)

Dilution: WB 1:500~1:1000 IHC 1:1000~1:2000

Purification: Affinity-chromatography

Specificity: Histone H3 (mono+di+tri methyl K79) Antibody detects endogenous levels of total Histone H3 (mono+di+tri methyl K79)

Molecular Weight: 15kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P68431

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only