Product Description

Histone H3 (mono methyl R17) Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40083-50, BS40083-100

Swiss-Prot: P68431

Host: Rabbit

Histone H3 (mono methyl R17) Rabbit Monoclonal Antibody-BS40083

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF

All Applications: WB 1:100~1:2000 IHC 1:100~1:250 ICC/IF 1:100~1:250

Background: H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.

Purification and Purity: Affinity-chromatography

Specificity: Histone H3 (mono methyl R17) Antibody detects endogenous levels of total Histone H3 (mono methyl R17)

Bioworld Molecular Weight: 15kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Histone H3 (mono methyl R17) expression in HeLa cell lysate., Immunohistochemical analysis of paraffin-embedded mouse colon, using Histone H3 (mono methyl R17) Antibody.

Alternative Name: H3 histone; HIST1H3A; Histone cluster 1, H3a; H3R17me1

Immunogen: A synthesized peptide derived from human Histone H3 (mono methyl R17)

Modification: Unmodified

Conjugate: Unconjugated