Product Description

Histone H3 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65953-50, MB65953-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template. Histones thereby play a central role in transcription regμlation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regμlated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, IF/ICC, IP

Alternate Names: HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, HIST2H3A, HIST2H3C, H3F2, H3FM, HIST2H3D, Histone H3.2, Histone H3/m, Histone H3/o, H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B, Histone H3.3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein corresponding to human Histone H3.

Dilution: WB (1/2000 - 1/5000), IF/ICC (1/100 - 1/500), IP (1/50 - 1/200)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Histone H3 protein.

Molecular Weight: ~ 16 kDa

Pathway: MAPK Erk in Growth and Differentiation Pathway(, NF-kB Signaling, Signaling Pathways Activating p38 MAP Kinase

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P68431, Q71DI3, P84243

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only