Product Description

HKR1 (W154) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1923-50, BS1923-100

Sizes: 50µl, 100µl

Swiss-Prot: P10072

Host: Rabbit

Reactivity: Humam

Applications: WB, IHC

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: HKR1 (W154) polyclonal antibody detects endogenous levels of HKR1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HKR1 (W154) pAb at 1:1000 dilution
Lane 1: HEK293T whole cell lysate (20ug)
Lane 2: A549 whole cell lysate (40ug)
Lane 3: PC3 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of HKR1 (W154) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 73 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Krueppel-related zinc finger protein 1; Protein HKR1; Zinc finger protein 875; HKR1; ZNF875

Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human HKR1.

Conjugate: Unconjugated

Modification: Unmodified