Product Description

HLA DMB Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS48999-50, BS48999-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecμle is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellμlar vesicles. DM plays a central role in the peptide loading of MHC class II molecμles by helping to release the CLIP (class II-associated invariant chain peptide) molecμle from the peptide binding site. Class II molecμles are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellμlar domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP

Alternate Names: RING7, D6S221E

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human HLA DMB

Dilution: WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 29 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P28068

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only