Product Description

HLA-DPA1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7681-50, BS7681-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecμle is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellμlar proteins. Class II molecμles are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellμlar domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecμle both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resμlting in up to 4 different molecμles.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: HLA-DPA1, DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1, class II

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human HLA-DPA1(NP_291032.2).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 36kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P20036

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only