HLA-DPA1 Polyclonal Antibody - E-AB-18082

HLA-DPA1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18082-60, E-AB-18082-120, E-AB-18082-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HLA-DPA1

Target Synonym: DP(W3); DP(W4); HLA class II histocompatibility antigen DP alpha 1 chain; HLA class II histocompatibility antigen DP alpha chain ; HLA DP1A; HLA DPA 1; HLA SB alpha chain; HLADP; HLADPA1 ; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha gene; Major histocompatibility complex class II DP alpha 1; MHC class II antigen; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA DPA1 antigen; PLT1; Primed lymphocyte test 1

Research Areas: Cancer, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P20036

Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Concentration: 0.96 mg/mL

Immunogen: Synthetic peptide of human HLA-DPA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Calculated MW: 29 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only