Product Description

HLA-DQA1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6917-50, BS6917-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecμle is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellμlar proteins. Class II molecμles are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellμlar domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecμle both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resμlting in up to four different molecμles. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: HLA-DQA1, CELIAC1, DQ-A1, HLA-DQA, CD, GSE, class II

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human HLA-DQA1(NP_002113.2).

Dilution: WB, 1:500 - 1:2000 IHC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 28kDaa-37kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01909

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only