Product Description

HLA-DR Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65810-50, MB65810-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Major histocompatibility complex class II (MHC class II) molecμles are heterodimeric, transmembrane glycoproteins expressed on the surface of antigen-presenting cells such as macrophages, dendritic cells, and B cells. Expression can also be induced on other cell types through interferon-γ signaling. Prior to being displayed on the cell membrane, MHC class II molecμles are loaded with exogenous peptide antigens approximately 15-24 amino acids in length that were derived from endocytosed extracellμlar proteins digested in the lysosome. Antigen-presentation through MHC class II is required for T cell activation during the immune response to extracellμlar pathogens. In humans, the MHC class II protein complex is encoded by the human leukocyte antigen gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IF, FC

Alternate Names: HLA-DRA1, HLA class II histocompatibility antigen. DR alpha chain, MHC class II antigen DRA

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Native purified human HLA-DR.

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human HLA-DR

Molecular Weight: ~ 28 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01903

Product: Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only