HLA-F Monoclonal Antibody - BT-MCA2806

HLA-F Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2806-50, BT-MCA2806-100

Citations, Manuals and MSDS Available upon request.

Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

Research Areas: Others

Target Protein: HLA-F

Applications: WB, FCM

Clonality: Monoclonal

Clone ID: 3F11F4

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: HLA-F

Immunogen: Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 39kDa

UniProt Accession: P30511

Synonyms: HLAF, CDA12, HLA-5.4, HLA-CDA12

GeneID: 3134

Research Use Only