Product Description

HLA-H (I104) Polyclonal Antibody

Catalogue Numbers: BS3876-50, BS3876-100

Sizes: 50µl, 100µl

Alternative Name: Hereditary hemochromatosis protein; HLA-H; HFE; HLAH

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q30201

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HLA-H (I104) polyclonal antibody detects endogenous levels of HLA-H protein.

Bioworld Molecular Weight: ~ 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HLA-H (I104) pAb at 1:1000 dilution
Lane 1: Hela whole cell lysate(10ug)
Lane 2: H1792 whole cell lysate(40ug)
Lane 3: The Heart tissue lysate of Mouse(40ug)
Lane 4: The Heart tissue lysate of Rat(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 72-126 of Human HLA-H.

Conjugate: Unconjugated

Modification: Unmodified